Uses Uses Aspirin is used to reduce fever and relieve mild to moderate pain from conditions such as muscle aches, toothachescommon coldand headaches. It may also be used to reduce pain and swelling in conditions such as arthritis.
In this experiment aspirin, also known as acetylsalicylic acid, was synthesized from salicylic acid and acetic anhydride. In the reaction the hydroxyl group on the benzene ring in salicylic acid reacted with acetic anhydride to form an ester functional group.
This method of forming acetylsalicylic acid is an esterification reaction. Since this esterification reaction is not spontaneous, sulfuric acid was used as a catalyst to initiate the reaction.
Crystallization, which uses the principle of solubility, was then used to remove most of the impurities and caused the acetylsalicylic acid to precipitate out of the solution.
Next, the crude product was then purified by adding water which further lowered the solubility of acetylsalicylic acid and dissolved some impurities from the crystal of aspirin. The aspirin was then isolated from the solution using a vacuum filtration apparatus. The percent yield of crude aspirin product was To purify the crude aspirin product a recrystallization procedure was performed.
The percent yield of the purified aspirin product Asprin lab 5. Next a phenol test was Asprin lab on the crude aspirin product, the purified aspirin product, and salicylic acid as a control.
The phenol test was to test the purity of the aspirin product that was created during the experiment. The crude aspirin product and the purified aspirin product had no color changes and remained orange when mixed with the iron III chloride solution, which means that there were no phenol groups in both the crude aspirin product and the purified aspirin product.
The lack of reaction with the iron III chloride revealed that both the crude aspirin product and the purified aspirin product were pure aspirin.
The salicylic acid turned into a dark purple color when mixed with the iron III chloride solution, which was expected since salicylic acid has phenol groups. Next a melting point test was performed on the purified aspirin product. The purified product started to melt at 86 degrees Celsius and finished completely melting at degrees Celsius.
The melting point of the purified product was lower than the expected degree Celsius melting point of aspirin, which revealed to us that the purified aspirin product still contained some impurities. As early as BC ancient cultures such as Greek, Roman, Egyptian, and Chinese found that extracts from plants such as willow bark, meadowsweet, and myrtle possessed the ability to alleviate fever, pain, and inflammation.
These plants contain a compound called salicylate, which creates these curative attributes. Several of years later the folk remedy of plants containing salicylate transformed into the cure-all medication known as aspirin.
Today aspirin, also known as acetylsalicylic acid, is an over the counter medication that is extremely popular and is used for relieving pain, reducing fever, reducing swelling, and slowing blood clotting. The history of aspirin began in when Edward Stone wrote a paper to the Royal Society of London that claimed that willow bark could cure ague, which is now known as malaria.
Later it was found that the treatment did not actually cure malaria, but instead just reduced the fever of those with the disease.
Lab Report Introduction This lab has the following two concepts: synthesis of acetylsalicylic acid and analysis of acetylsalicylic acid. Synthesis is a purposeful execution of chemical reactions to obtain a product. This concept is used in the first part of the lab; when we have to produce crystals of leslutinsduphoenix.comis is the separation, identification, and quantification of the chemical. 1 Determination of Aspirin using Back Titration This experiment is designed to illustrate techniques used in a typical indirect or back titration. You will use the NaOH you standardized last week to back titrate an aspirin solution and determine the concentration. Los Angeles City College Chemistry 51 Fall 1 Experiment 11 Synthesis and Analysis of Aspirin INTRODUCTION Aspirin is most widely sold over-the-counter drug. It has the ability to reduce fever (an antipyretic), to.
Organic chemists began working with willow bark and many other plants to try and extract and isolate the active ingredients from them, in doing so it was found that the active ingredient was salicylic acid. Salicylic acid was then industrialized for medicinal use, but soon after industrialization it was found that salicylic acid was extremely limited as a treatment because of the acidic properties that cause severe irritation in the digestive tract.
InFelix Hofmann synthesized acetylsalicylic acid, which has all of the same medicinal benefits as salicylic acid but it did not have the side effect of irritating the digestive tract. Hofmann worked for Bayer, which then named acetylsalicylic acid compound aspirin.
Aspirin became commercially available in and today it is estimated that over a trillion aspirin tablets have been consumed by those in need of its curative effects. In this experiment aspirin was synthesized from salicylic acid and acetic anhydride.
Salicylic acid was esterfied using acetic acid and sulfuric acid acting as a catalyst to produce acetylsalicylic acid and acetic acid.
The phenol group that will attack the carbonyl carbon of the acetic anhydride is the —OH group that is directly attached to the benzene since it is more basic than the —OH group attached to the carbonyl group.Transcript of Aspirin Synthesis Lab Report Aspirin Synthesis Lab By Abigail Arrigo, Alexis Arrigo, Christian Bruns, Alissa Lockwood, and Justin Rose Objective 1 The first objective of this lab was to synthesize aspirin and perform a purity test on the product.
The Synthesis of Aspirin Chemistry Standard Level Lab Report Data Collection and Processing and Conclusion and Evaluation Date: December 8th, Purpose: The purpose of this lab was to synthesize aspirin, determine the theoretical yield, compare the percent yield to the theoretical yield and test the purity of aspirin by adding Iron (III.
The goal of this experiment was to synthesize aspirin.
In this experiment aspirin, also known as acetylsalicylic acid, was synthesized from salicylic acid and acetic anhydride.
In the reaction the hydroxyl group on the benzene ring in salicylic acid reacted with acetic anhydride to form an ester functional group.
This method of forming acetylsalicylic acid [ ]. Aspirin is the common name for the compound acetylsalicylic acid, widely used as a fever reducer and as a pain killer.
Salicylic acid, whose name comes from Salix . The medicinal properties of acetylsalicylic acid have been known for millenia - Aspirin lab introduction. The ancient Greeks noted that extracts of willow and poplar bark were effective painkillers, though it was not until the s that its active ingredient, salicylic acid, was isolated.
However, it was strongly acidic and irritated membranes of the mouth. Lab Report Introduction This lab has the following two concepts: synthesis of acetylsalicylic acid and analysis of acetylsalicylic acid.
Synthesis is a purposeful execution of chemical reactions to obtain a product. This concept is used in the first part of the lab; when we have to produce crystals of leslutinsduphoenix.comis is the separation, identification, and quantification of the chemical.